megatomi.com Secrets
megatomi.com Secrets
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Our new Very clear+ tissue clearing procedure is the only real method that delipidates samples with no modify in morphology and with small influence on structural integrity.
Megatome is a vibrating microtome created to segment a wide variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform area profile, as well as minimal tissue harm and information reduction.
Antibodies may well choose months to diffuse by just a few millimeters of tissue, by using a steep labeling gradient from area to Main.
Megatome is suitable for precision: the blade vibrates at an increased frequency and larger amplitude selection than other microtomes, and incorporates a exclusive deflection Regulate mechanism.
SE makes use of a rotational electric field to disperse highly electromobile molecules (which include antibodies or surfactant micelles) in the course of a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 working day clearing of intact organs,
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Megatome is often a novel microtome that permits for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue injury and information reduction.
eFLASH is really a immediate tissue labeling approach which allows for uniform total-organ staining in 20 rounds of labeling.
The SmartSPIM gentle sheet microscope supplies unparalleled resolution and acquisition velocity all over intact tissue volumes, while its modular style permits you to improve and customise person factors.
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Either obtain a launch or create a distribution zip as outlined over. Unzip the archive to your wished-for place.
Leverage the Apparent+ tissue clearing strategy, together with eFLASH and patented stochastic electrotransport technologies, to promptly very clear and label total organs. Critical highlights and features consist of:
Our novel Defend tissue preservation strategy varieties intramolecular bonds applying polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.